Injectable Micronutrient Treatment

Mesotherapy London

Facial Skin Rejuvenation in Harley Street

Nourish · Brighten · Revitalise

Defined by Paris — Perfected by Seoul — Excellence on Harley Street

22 Harley Street · CQC Regulated · Face & Body · All Skin Tones · The French Touch

Mesotherapy bypasses the skin’s surface barrier entirely — delivering a precisely formulated cocktail of vitamins, minerals, antioxidants, and active ingredients directly into the dermis, where they can act on living skin cells at full potency.

What Is Mesotherapy?

Developed in France in the 1950s, mesotherapy is one of the most established injectable treatments in aesthetic medicine. A series of superficial microinjections delivers a bespoke blend of active ingredients — including vitamins B, C, and E, hyaluronic acid, amino acids, minerals, and plant extracts — directly into the mesoderm (middle layer of the skin), where topical products, however sophisticated, cannot penetrate.

At PHP Aesthetic-Wellness, mesotherapy formulas are selected and compounded specifically for each patient’s skin concern — whether that is facial rejuvenation, brightening and pigmentation, hair loss, body contouring, or scalp health. The same fundamental technique is adapted across a wide range of clinical applications, making mesotherapy one of the most versatile tools in our treatment repertoire.

“Mesotherapy is the treatment that makes other treatments work better. By delivering exactly what the skin needs directly where it needs it, we create the biological conditions for lasting improvement — not just surface radiance that fades in days.”PHP Aesthetic-Wellness, 22 Harley Street

Mesotherapy Applications

Facial Rejuvenation

A cocktail of hyaluronic acid, vitamins, and antioxidants restores hydration, luminosity, and skin vitality — the most requested mesotherapy application. Results are visible after the first session and build progressively over a course.

Pigmentation & Brightening

Vitamin C, glutathione, and tranexamic acid delivered directly into the dermis interrupt melanin synthesis, fade existing pigmentation, and restore an even, luminous complexion. Particularly effective for post-inflammatory hyperpigmentation and melasma.

Hair Loss & Scalp Health

A scalp-specific formula containing biotin, vitamins B5 and B6, zinc, copper peptides, and DHT-inhibiting agents is injected directly into the scalp dermis, stimulating follicular activity and improving scalp microcirculation. Often combined with PRP for enhanced results.

Body Contouring

Phosphatidylcholine, L-carnitine, caffeine, and circulatory agents emulsify localised fat deposits, improve lymphatic drainage, and reduce the appearance of cellulite in targeted body areas.

Skin Hydration & Quality

Hyaluronic acid and peptide-based formulas improve overall skin quality, texture, and resilience — used as a standalone treatment or to complement and extend the results of skin boosters and polynucleotides.

Benefits

Delivers active ingredients at full potency directly to target cells — bypassing the skin barrier

Instantly improves hydration, luminosity, and skin vitality

Reduces pigmentation and uneven tone through targeted tyrosinase inhibition

Stimulates hair follicle activity and scalp microcirculation

Supports fat reduction and lymphatic drainage in body applications

Minimal downtime — most patients return to normal activities the same day

Safe for all skin tones and Fitzpatrick types I–VI

Highly versatile — formula adapted to each patient’s specific concern

Treatment Protocol

💉

Facial Mesotherapy

A series of superficial microinjections across the face, neck, or décolleté. Topical anaesthetic cream applied 30 minutes before treatment ensures comfort. A mild flushing and pin-mark redness is normal and settles within a few hours.

30–45 min

Per session

4–6

Sessions typical

Minimal

Downtime

🧖

Body & Scalp Mesotherapy

Adapted formula and injection technique for the scalp, thighs, abdomen, and other body areas. Session length varies by treatment area. Results are progressive and most pronounced after a full course, combined with appropriate home care.

30–60 min

Per session

6–10

Sessions typical

24–48 hrs

Downtime

A note on mesotherapy for darker skin tones. Brightening mesotherapy formulas — particularly those containing vitamin C and glutathione — are safe and effective across all Fitzpatrick types. Formulas are adapted for each patient. Dr Hamida-Pisal and Dr Jihyun Byun have specific expertise in treating medium-to-deep skin tones and will select the most appropriate protocol for your complexion.

Frequently Asked Questions

Is mesotherapy painful?

Most patients find mesotherapy well tolerated. The injections are superficial and performed with very fine needles. A topical anaesthetic cream is applied 30 minutes before treatment to minimise discomfort. A mild stinging sensation during injection is normal and brief.

How soon will I see results?

Many patients notice improved hydration and luminosity within 24–48 hours of their first session. Pigmentation, hair loss, and body applications respond more gradually — significant results typically become apparent after three to four sessions, with the full benefit of a course visible at six to eight weeks.

How is mesotherapy different from skin boosters?

Skin boosters deliver a single active ingredient — hyaluronic acid — at a deeper dermal level for lasting hydration. Mesotherapy delivers a cocktail of multiple active ingredients at a more superficial level, targeting a wider range of skin concerns simultaneously. The two are frequently combined for complementary results.

Can mesotherapy be used for hair loss?

Yes — scalp mesotherapy is a well-established and effective treatment for androgenetic alopecia, female pattern hair loss, and telogen effluvium. It delivers DHT-inhibiting agents, follicle-stimulating vitamins, and circulation-enhancing compounds directly to the scalp dermis, bypassing the barrier that prevents topical products from reaching the follicle effectively.

Are there any contraindications?

Mesotherapy is not suitable during pregnancy or breastfeeding, or in patients with active skin infection at the treatment site. Those with a known allergy to any component of the formula should discuss this at consultation. Patients on blood-thinning medications should inform the clinic as this may increase bruising.

Related Treatments

💧

Skin Boosters

Deep hyaluronic acid hydration that complements mesotherapy — skin boosters work at a deeper dermal level for lasting structural moisture improvement.

Learn more →

🔬

Polynucleotides

Structural dermal repair that reinforces and extends the results of a mesotherapy course, building collagen and elastin in the same tissue.

Learn more →

🩸

PRP

Platelet-rich plasma — the patient’s own growth factors applied alongside mesotherapy for hair loss and skin rejuvenation for a combined regenerative effect.

Learn more →

What our clients say

      EXCELLENT  
   Based on 155 reviews 
    
 
 
 
   
 
 
       Posted on Google  
   
   Ana M. Pastor 
 
 
 
 Trustindex verifies that the original source of the review is Google. Auf Empfehlung einer Freundin habe ich den Weg aus der Schweiz auf mich genommen, und jeder Kilometer hat sich gelohnt. Bei Dr. Philippe habe ich mich von Anfang an in besten Händen gefühlt: professionell, einfühlsam und präzise, mit einem Ergebnis, das natürlich und mühelos schön wirkt.
Von Herzen vielen Dank an ihn und PHP Aesthetic!
  
 
      Posted on Google  
   
   Steven Barclay 
 
 
 
 Trustindex verifies that the original source of the review is Google. Always a great experience and professionally led by Phillipe
  
 
      Posted on Google  
   
   Emily Kanauros 
 
 
 
 Trustindex verifies that the original source of the review is Google. 
  
 
      Posted on Google  
   
   Natasha H 
 
 
 
 Trustindex verifies that the original source of the review is Google. Amazing! Fabulous kind team that don’t push sales or products. If you want to feel like the best version of yourself he’s the man for you, he always makes me feel ‘less tired’. A fabulous safe pair of hands - best anti aging / refreshing team in the business. Thank you Dr Philippe to you and your team - wonderful as always !
  
 
      Posted on Google  
   
   Sarah Plane 
 
 
 
 Trustindex verifies that the original source of the review is Google. Great consultation with no pressure to go ahead. Relaxed and non-rushed appointment.
  
 
      Posted on Google  
   
   Alla Giddings 
 
 
 
 Trustindex verifies that the original source of the review is Google. 
  
 
      Posted on Google  
   
   Mahmoud Charari 
 
 
 
 Trustindex verifies that the original source of the review is Google. The best clinic
  
 
      Posted on Google  
   
   Cecilia Puga 
 
 
 
 Trustindex verifies that the original source of the review is Google. Always a fantastic experience at PHP. I highly reccomend their treatments to anyone looking for a youthful skin glow & tone. I’m looking forward to my next visit.
  
 
      Posted on Google  
   
   Sarah Evitt 
 
 
 
 Trustindex verifies that the original source of the review is Google. I always look forward to seeing Dr. Phillipe. The clinic has such a warm, friendly and relaxing atmosphere. I have had many treatments all of which  I have been more than happy with. Cannot recommend PHP Aesthetics high enough!
  
 
      Posted on Google  
   
   Gail Hendry 
 
 
 
 Trustindex verifies that the original source of the review is Google. Lovely friendly place .And very professional thank you so much my Botox .Wonderful as always x